Physical properties and biocompatibility of an injectable calcium-silicate-based root canal sealer: in vitro and in vivo study
نویسندگان
چکیده
BACKGROUND The aim of this study was to investigate the physical properties and biological effects of an experimentally developed injectable premixed calcium-silicate root canal sealer (Endoseal) in comparison with mineral trioxide aggregate (MTA) and a resin-based sealer (AHplus). METHODS The pH, solubility, dimensional change, flow, and radiopacity of the materials were evaluated. Biocompatibility was evaluated on the basis of cell morphology and a viability test using MC3T3-E1 cells. For evaluate inflammatory reaction, the tested sealers were implanted into dorsal subcutaneous connective tissue of Sprague Dawley rats. After 7 days, the implants with the surrounding tissue were retrieved, and histological evaluation was performed. RESULTS Endoseal showed high alkalinity similar to that of MTA. The solubility of the tested materials was similar. The dimensional change and flow of Endoseal was significantly higher than that of other materials (P < 0.05). The radiopacity of Endoseal was lower than that of AHplus (P < 0.05). The biocompatibility was similar to those of MTA. Inflammatory reaction of Endoseal was similar with that of MTA, but lower than that of AHplus (P < 0.05). CONCLUSIONS The present study indicates that Endoseal has favorable physical properties and biocompatibility. Therefore, we suggest that Endoseal has the potential to be used as a predictable root canal sealer.
منابع مشابه
Composition and physicochemical properties of calcium silicate based sealers: A review article
Background Recently a new generation of endodontic sealers has been developed based on calcium silicate as MTA Fillapex, Endoseal MTA, Total Fill BC Sealer, EndoSequence BC Sealer, iRoot SP, Endo CPM sealer, MTA-Angelus and ProRoot Endo Sealer. A review of literature was conducted to discuss the composition, physicochemical properties, and clinical perspectives of calcium silicate based sealers...
متن کاملGenotoxicity, Bioactivity and Clinical Properties of Calcium Silicate Based Sealers: A Literature Review
An ideal endodontic sealer should have many properties such as excellent seal after setting, dimensional stability, slow setting time to ensure sufficient working time, insolubility to tissue fluids, adequate adhesion with canal walls and biocompatibility. Genotoxicity is one of the important factors that influence biocompatibility of an endodontic sealer. This literature review was conducted t...
متن کاملEx-vivo Apical Seal Comparison of Root Canal Obturation Using MTA Fillapex Versus MTA Orthograde
Introduction: Mineral trioxide aggregate (MTA) as an alternative material to gutta-percha for obturation of root canal in special cases has several drawbacks. The purpose of this study was to compare the apical sealing ability of a new MTA-based sealer versus MTA. Materials and Methods: A total of 36 canals of extracted maxillary central incisors were instrumented and randomly divided into 3...
متن کاملResistance to fracture of roots filled with different sealers.
The aim of this study was to compare the fracture resistance of roots filled with gutta percha (GP) and different root canal sealers.Fifty-five human maxillary central incisors were selected and randomly divided into three experimental groups (Groups 1-3) and two control groups (Groups 4 and 5). They were Group 1-15 root canals filled with an epoxy resin-based sealer (AH Plus) and GP, Group 2 -...
متن کاملEffects of calcium hydroxide addition on the physical and chemical properties of a calcium silicate-based sealer
UNLABELLED Recently, various calcium silicate-based sealers have been introduced for use in root canal filling. The MTA Fillapex is one of these sealers, but some of its physicochemical properties are not in accordance with the ISO requirements. OBJECTIVE The aim of this study was to evaluate the flowability, pH level and calcium release of pure MTA Fillapex (MTAF) or containing 5% (MTAF5) or...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 15 شماره
صفحات -
تاریخ انتشار 2015